OTC Ophthalmics
Soothe®XP Emollient (Lubricant) Eye Drops
Key Features & Benefits
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The oil-based emulsion, Restoryl® , adds oils to the outer lipid layer, which forms a seal
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Rebuilds the entire tear film
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Relief that lasts up to 8 hours
Product Detail Information
Bausch & Lomb Soothe®XP Emollient (Lubricant) Eye Drops give your patients rapid relief of dry eye symptoms that lasts up to 8 hours. Ordinary lubricant eye drops simply provide moisture which can evaporate quickly from the surface of the eye. Only SootheXP has Restoryl® , a special oil-based emulsion that delivers moisture and the lipid replacements that help retain it for up to 8 hours of relief. Because the outer lipid layer is oil-based, moisture won't evaporate through.
Upon application, patients may experience momentarily blurred vision as SootheXP eye drops seal in moisture.
This is the formulation previously owned and marketed by Alimera Sciences.

Tear Film Lipids
Research has revealed a great deal about the tear film. The model of the tear film as a three-layer barrier that provides a smooth refracting surface, preventing evaporation is still essentially correct. But the components interact in many interesting ways, and each layer is tremendously more complex than once thought.
Read more about the complexities of the tear film
Lipid Layer Papers
Review, download and print these articles originally published as supplements to Refractive Eyecare:
Managing the Lipid Layer in Ocular Surface Disease
Volume 10, Number 6, June 2006
The Therapeutic Role of Lipids
Volume 9, Number 6, June 2005
Title: Drops significantly increase lipid layer thickness, study finds. Instillation of one drop increased thickness of lipid layer by 110% from baseline in trial.
Author: Lynda Charters (Reviewed by Donald R. Korb, OD)
Source: Ophthalmology Times - September 1, 2005
Clinical Posters
Title: Increased Tear Film Lipid Layer Thickness With The Use Of
Two Novel Lubricant Eye Drops
Presented At: TFOS, November 2004
Purpose: Tear film lipid layer thickness (LLT) has been correlated to the presence of dry eye symptoms. Two novel products, Soothe® and Systane®, were studied to determine if a single drop of either product produce a significant increase in LLT.
Patient Profiles
SootheXP is commonly used by people experiencing excessive tearing, dry, burning or irritated eyes related to:
- Hormone replacement therapy
- Recent LASIK surgery
- Excessive computer use
- Nasal corticosteroid or antihistamine use
- Birth control pill use
- Antidepressant use
- Beta blocker and/or diuretic use